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Chemical Constituents of the Anemone tomentosa Root

WANG Jun-Ru; PENG Shu-Lin; WANG Ming-Kui;FNG Jun-Tao ;DING Li-Sheng(Laboratory of Natural Materia Medica,Chengdu Institute of Biology,The Chinese Academy of Sciences,Chengdu 610041)(Department of Basic Sciences,Northuestern Agricultural University,Yangli  
The roots of Anemone tomentosa (Maxim. ) Pei (Ranunculaceae) have been used as traditional medicine for the treatment of dysentery, infantile malnutrition, carbuncles, etc. Ethyl acetate extract of the roots displaied stronger antifeedant activity against Leucania separata Walker. Eleven compounds were isolated by silica gel columm chromatography from the extract and their structures were identified as 4,5-dimethoxyl-7-methyl-coumarin (1 ), 4-methoxyl-5(methyl-6, 7 - methylenedioxy- coulnarin (2 ), 4, 7 - dimethoxyl- 5 - methylcotnnarin (3), oleanolic arid (4), oleanonic acid (5), 3--O-5-D-xylopyranosyl oleanolic acid (6), -sitosterol (7), stigmaSterol (8), daucosterol (9), 3 - O-5- D- glucopystigmasterol (10 ) and egrterol pemtide (11) respectively on the baSis of special evidence. Compounds 1 and 2 are new naed products.
【Fund】: 中国科学院成都地奥科学基金
【CateGory Index】: Q946
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