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《Acta Botanica Sinica》 2001-01
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New Steroidal Glycosides from Ophiopogon japonicus

DAI Hao_Fu 1, ZHOU Jun 1 *, TAN Ning_Hua 1, DING Zhong_Tao 2 [WT6BZ](1. Laboratory of Phytochemistry, Kunming Institute of Botany, The Chinese Academy of Sciences, Kunming 650204, China; 2. Department of Chemistry, Yunnan University, Kunming 65009  
Two new C 27 steroidal glycosides, named ophiopojaponin A (1) and B (2), together with two known ones, were isolated from the tubers of the famous traditional Chinese herb Ophiopogon japonicus Ker_Gawl. The spectroscopic and chemical evidence revealed their structures to be pennogenin 3_O_[2′_O_acetyl_α_L_rhamnopyranosyl (1→2)]_β_D_xylopyranosyl (1→3)_β_D_glucopyranoside (1), 26_O_β_D_glucopyranosyl_(22ξ, 25R)_3β, 14α, 22ξ, 26_tetrahydroxyfurost_5_ene 3_O_α_L_rhamnopyranosyl (1→2)_β_D_glucopyranoside (2), diosgenin 3_O_[α_L_rhamnopyranosyl (1→2)]_β_D_xylopyrano_syl (1→3)_β_D_glucopyranoside (3) and ruscogenin 1_O_[α_L_rhamnopyranosyl (1→2)]_β_D_xylopyranosyl (1→3)_β_D_fucopyranoside (4).
【Fund】: SupportedbyakeyprojectoftheChineseAcademyofSciences (KZ 95 2_J1_111) .
【CateGory Index】: Q946.8
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【References】
Chinese Journal Full-text Database 1 Hits
1 WANG Qiong1,WANG Zhen1,TAN Ning-hua2(1.Institute of Yunnan Baiyao Academy,Kunming 650032,China;2.Phytochemisty and Plant Resources in West China,Kunming Institute of Botany,Chinese Academy of Sciences,Kunming 650204,China);An NMR Study on Two Semi-Synthetic Pennogenin Saponins[J];Chinese Journal of Magnetic Resonance;2010-04
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 Liu Bing; Wu Guangheng(Department of Medical Genetics);Study on the genetic toxicity of Radix Ophiopogonis[J];JOURNAL OF NORMAN BETHUNE UNIVERSITY OF MEDICAL SCIENCE;1999-02
2 ZHU Yu zhuo 1,PANG Hui min 1,LIU Nian zhi 2 (1. Dept.of Medical Genetics,School of Basic Medical Sciences,Jilin University, Changchun 130021,China;2.The People Hospital of Jilin Province);Inhibitory effect of Radix ophiopogonis on unscheduled DNA synthesis induced by methyl methanesulfonate in spermatogod of mice[J];Journal of Norman Bethune University of Medical Science;2002-05
3 Yang Peiman,Ao Xiang,Yu Limin Dalian Medical College;THE STUDY OF INDUCING DIFFERENTIATION OF HL_(60) CELL LINE BY USING OF LIRIOPE SPICATA LOUR[J];;1992-04
4 Hao Fu DAI, Jun ZHOU1, Zhong Tao DING, Jiang XIONG, Ning Hua TAN (Laboratory of Phytochemistry, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204) (Department of Chemistry, Yunnan University, Kunming 650091);Two New Steroidal Glycosides from Ophiopogon japonicus[J];中国化学快报(英文版);2000-10
5 CHEN Dao-liang,WAN Long\;(Fujian Institute of TCM & Pharmacology,FCTCM,Fuzhou,Fujian 350003,China) \;;Observation on Effects of Combination of Radix Ophiopogonis and Calcium Channel Blockers to Prevent Side Effects of Isoprenaline[J];Journal of Fujian College of Traditional Chinese Medicine;2001-01
6 ZHANG Shou-Qin, ZHANG Jin-Song, WANG Chang-Zheng (College of Biology and Agricultrue Engineering, Jilin University, Changchun 130 025, China);Synthesis of Pennogenyl Saponins via Three Methods[J];Chemical Journal of Chinese Universities;2007-03
7 WANG Heng-shan 1, TAN Ming-xiong 2, GONG Chong-song 1, CHEN Wei -sheng 1, LI Shuang 3, LI Guang-zhao 4 ( 1.Department of Chemistry and Chemical Engineering, Guangxi Nomal Univercity, Guilin 541004, China; 2.Department of Chemistry and Biology, Yulin Normal College, Yulin 53700, China; 3.The Inspector of Medicine Department of Guilin, Guilin 541002, China; 4.Guangxi Insitute of Botany, Guangxi Zhuangzu Autonomous Region and Academia Sinica, Guilin 541006, China );Quality and quantity determination of one steroidal sapogenin of Aspidistra retuda[J];Guihaia;2003-05
8 Yang Zhi Xiao Rong Xiao Zhuo-YiN(Institute of Meteria Medica, West China university of Medical Sciences Chengdu);STUDY ON CHEMICAL CONSTITUENTS OF OPHIOPOGONIS JAPONICUS (THUMB) OF SICHUAN(1)[J];West China Journal of Pharmaceutical Sciences;1987-02
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【Secondary References】
Chinese Journal Full-text Database 1 Hits
1 XIA Dao-zong1, YU Xin-fen2, WANG Hui-ming1, JIANG Li-qin1, XIA Ming(1College of Pharmaceutical Sciences, Zhejiang University of Traditional Chinese Medicine, Hangzhou 310053, China;2Hangzhou Center for Disease Control and Prevention, Hangzhou 310006, China);Study on extraction conditions optimization of total flavonoids from Ophiopogon japonicus by response surface methodology and its antioxidant effects[J];China Journal of Traditional Chinese Medicine and Pharmacy;2009-12
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