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《Occupation and Health》 2012-01
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Clinical observation of phloroglucinol on obstetric process acceleration during active phase of labor

SONG Yan-fei,GAO Zhi-hua,CHEN Feng-yan Department of obstetrics and gynecology,Tianjin Haihe hospital,Tianjin,300350,China  
[Objective]To observe the effect of phloroglucinol on improving cervical dilatation and promoting the labor progress during active phase of labor. [Methods]185 normal term primipara with single pregnancy,head position,cervical dilatation greater than or equal to 3 cm,cervical toughness or cervical edema were collected from January 2008 to December 2010.They were randomly divided into three groups.In order to improving cervical dilatation,group A(62 cases) was treated with phloroglucinol 80 mg by intravenous injection during active phase of labor,group B(63 cases) was treated with 654-2 10 mg by intravenous injection slowly,and group C(60 cases) was treated with diazepam 10 mg by intravenous injection slowly(5 min).The labor progress,delivery mode,fetal distress and newborns Apgar score of three groups were observed. [Results]The duration from drug administration to full dilation of the cervix in group A was(8.2±1.7) h,and the average duration of the first stage of labor was(8.2±1.7) h,which were significantly shorter then than those in group B and group C(P0.05). [Conclusion]Phloroglucinol can alleviate the cervical edema,improve cervical dilatation and accelerate labor progress during active phase of labor,its effect is better than 654-2 and diazepam,and without adverse effect on mothers and fetuses.
【CateGory Index】: R714.3
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