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《Occupation and Health》 2012-04
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Effect of compound Tripterygium wilfordii formulation on laboratory indexes related to active rheumatoid arthritis

YE Sheng,HUANG Jian-hua,ZHANG Ping-an Department of Laboratory,Honghu TCM Hospital,Hubei,433200,China  
[Objective]To observe the effect of compound Tripterygium wilfordii formulation on erythrocyte sedimentation rate(ESR),C-reaction protein(CRP),antistreptolysin O(ASO),?rheumatoid factor(RF) and anti-cyclic citrullinated peptide antibody(anti-CCP) in patients with active rheumatoid arthritis(RA).[Methods]141 patients with active RA were divided into three groups(A,B and C) according to course of diseases,and each group was divided into damp-heat type and cold-dampness type.The patients of damp-heat type were treated by Huangteng liquor and arthromyodynia prescription 1 for 2weeks,and the patients of cold-dampness type were treated by Huangteng?liquor and arthromyodynia 1 prescription for 2weeks.The levels of ESR,CRP,ASO,RF and anti-CCP of the three groups were determined before and after treatment.[Results]After treatment,the levels of ESR,RF and CRP of three groups decreased obviously,and the differences were significant(P0.01 or P0.05).Among 10 positive anti-CCP cases,the levels of anti-CCP decreased significantly(P0.01).[Conclusion]The compound Tripterygium wilfordii formulation can improve the related laboratory indexes of RA patients,and has a definite effect on active rheumatoid arthritis.
【CateGory Index】: R259
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