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《Occupation and Health》 2012-04
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Effect of compound Tripterygium wilfordii formulation on laboratory indexes related to active rheumatoid arthritis

YE Sheng,HUANG Jian-hua,ZHANG Ping-an Department of Laboratory,Honghu TCM Hospital,Hubei,433200,China  
[Objective]To observe the effect of compound Tripterygium wilfordii formulation on erythrocyte sedimentation rate(ESR),C-reaction protein(CRP),antistreptolysin O(ASO),?rheumatoid factor(RF) and anti-cyclic citrullinated peptide antibody(anti-CCP) in patients with active rheumatoid arthritis(RA).[Methods]141 patients with active RA were divided into three groups(A,B and C) according to course of diseases,and each group was divided into damp-heat type and cold-dampness type.The patients of damp-heat type were treated by Huangteng liquor and arthromyodynia prescription 1 for 2weeks,and the patients of cold-dampness type were treated by Huangteng?liquor and arthromyodynia 1 prescription for 2weeks.The levels of ESR,CRP,ASO,RF and anti-CCP of the three groups were determined before and after treatment.[Results]After treatment,the levels of ESR,RF and CRP of three groups decreased obviously,and the differences were significant(P0.01 or P0.05).Among 10 positive anti-CCP cases,the levels of anti-CCP decreased significantly(P0.01).[Conclusion]The compound Tripterygium wilfordii formulation can improve the related laboratory indexes of RA patients,and has a definite effect on active rheumatoid arthritis.
【CateGory Index】: R259
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【Citations】
Chinese Journal Full-text Database 1 Hits
1 LI Na,JI Hong(Liaoning Unversity of Tradional Chinese Medicine,Shenyang 110032,Liaoning,China);Effection of Tripterygium Wilfordii Unions SASP Moves to Rheumatoid Arthritis[J];Journal of Liaoning University of Traditional Chinese Medicine;2008-12
【Co-citations】
Chinese Journal Full-text Database 4 Hits
1 Tang Xuemei(Children's Hospital of Chongqing Medical University,Chongqing 400014,China);Immunosuppressant on Pediatric Rheumatic Diseases[J];Journal of Pediatric Pharmacy;2011-03
2 XIE Hong-ming Yueyang Hospital of Traditional Chinese Medicine, Yueyang, Hunan, China, 414000;Study Progress in Treating Rheumatoid Arthritis of Bi Syndrome Induced by Wind、 Cold and Dampness with TCM[J];Guiding Journal of Traditional Chinese Medicine and Pharmacy;2009-04
3 LI Na,JI Hong(Liaoning Unversity of Tradional Chinese Medicine,Shenyang 110032,Liaoning,China);Effection of Tripterygium Wilfordii Unions SASP Moves to Rheumatoid Arthritis[J];Journal of Liaoning University of Traditional Chinese Medicine;2008-12
4 JIANG Quan,CAO Wei,TANG Xiaopo,Jiao Juan(Guang'anmen Hospital,China Academy of Chinese Medical Sciences,Beijing 100053,China);Tripterygium wilfordii extract for treating rheumatoid arthritis:Systematic review[J];China Journal of Chinese Materia Medica;2009-20
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