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《Acta Academiae Medicinae Sinicae》 2005-06
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Effect of Coeloglossum. viride var. bracteatum Extract on Oxidation Injury in Sub-acute Senescent Model Mice

Zhang Dan, Zhang Jian-jun# (Department of Pharmacology, Institute of Materia Medica, CAMS and PUMC, Beijing 100050, China)  
Objective To study the anti-aging effects of Coeloglossum. viride(L) Hartm. var. bracteatum(Willd)Richter extract(CE)on senescent model mice induced by D-galactose and sodium nitrite. Methods After one week of accommodation, 60 female NIH mice were divided into six groups with 10 mice in each group: normal control group, aging model group, Piracetam (positive control) group[300 mg/(kg·d)], and CE reatment groups?眼2.5, 5, and 10 mg/(kg·d)]. Mice in aging model group, Piracetam group, and CE treatment group were consecutively intraperitoneally injected with D-galactose[120 mg/(kg·d)]and sodium nitrite[90 mg/(kg·d)]for 60 days. From day 47, mice in Piracetam group and CE treatment group were po given Piracetam 300 mg/(kg·d) or CE 2.5, 5, and 10 mg/(kg·d). Mice in normal control group and aging model group were po given saline. The drug administration lasted for 14 days. Water maze test was performed to evaluate the learning and memory function in the mice. The activity of superoxide dismutase(SOD), the content of malondialdehyde(MDA), and the activities of adenosinetriphosphatase(ATPase), and monoamine-oxidase(MAO)in brain tissue were measured. Results The latencies in water maze test in aging model group mice were significantly longer than in normal control group(P 0.01,P 0.05), and the number of errors increased(P 0.05). In aging model group mice, the activities of SOD,Na+K+-ATPase, and Ca2+Mg2+-ATPase decreased(P 0.01,P 0.05), while the content of MDA and the activities of MAO-A and MAO-B increased(P 0.01). Piracetam[300 mg/(kg·d), po]and CE[2.5, 5, 10 mg/(kg·d), po]ameliorated the above changes in aging model mice. Conclusion CE may improve the memory dysfunction induced by consecutive injection of D-galactose and sodium nitrite, and has nootropic and antiaging effects.
【CateGory Index】: R29
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【References】
Chinese Journal Full-text Database 4 Hits
1 QIN Xiao-yan,LI Rong-chang,YUN Miao-ying,TANG Li,YAN Li,DAI Jin-feng(College of Life & Environmental Science,Central University for Nationalities,Beijing,100081);Effect of Tibetan medicine Wangla water-decoction on the immunological function of mice[J];Shandong Journal of Traditional Chinese Medicine;2007-12
2 ZHAO Yan-xia;DENG Yan-ru;ZHANG Xiao-jing;CHEN Fang;Tianjin Key Laboratory of Chinese Medicine Chemistry and Analysis,Tianjin University of Traditional Chinese Medicine;;Advances in Chemical Constituents and Pharmacology of Genus Bletilla[J];Natural Product Research and Development;2013-08
3 YUE Zhenggang,ZI Jiachen,ZHU Chenggen,LIN Sheng,YANG Yongchun,SHI Jiangong(Institute of Materia Medica,Chinese Academy of Medical Sciences and Peking Union Medical College,Key Laboratory ofBioactive Substances and Resources Utilization of Chinese Herbal Medicine,Ministry of Education,Beijing 100050,China);Constituents of Gymnadenia conopsea[J];China Journal of Chinese Materia Medica;2010-21
4 QIN Xiao-yan,YUN Miao-ying,TANG Li,YAN Li,DAI Jing-feng(College of Life and Environmental Sciences,Central University for Nationalities,Beijing 100081,china);Progress in the Research on Chemical Constituents and Pharmacological Activities of Coeloglossum[J];Journal of the Central University for Nationalities(Natural Sciences Edition);2007-03
【Citations】
Chinese Journal Full-text Database 2 Hits
1 BX Wang and XG Chen (Department of Pharmacology, Academy of Traditional Chinese Medicine and Materia Medica of Jilin Province,Changchun 130021);INHIBITORY EFFECT OF HYPOXANTHINE ON MONOAMINE OXIDASE ACTIVITY[J];Acta Pharmaceutica Sinica;1989-08
2 LUO Huan min,CHEN Zi sheng(Department of Pharmacology, College of Pharmacy, Jinan University, Guangdong Guangzhou 510632);A novel animal model of Alzheimer's disease[J];Chinese Journal of Gerontology;2003-03
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 ZHOU Ran et al(School of Chemical Engineering,Shijiazhuang University,Shijiazhuang,Hebei 050035);Study on the Extraction Process of Three Biological Bases from Antler Velvet[J];Journal of Anhui Agricultural Sciences;2011-35
2 Jin Yi Institute of Preclinical Science,Norman Bethune University of Medical Sciences;EFFECT OF SELENIUM AND VITAMIN E ON MONO AMINES AND MONOAMINE OXIDASE[J];Chinese Journal of Control of Endemic Disease;1997-02
3 Zhou Haiou~*, You Gengye, Chert Xiaoguang, Liu Shiyue, Wang Benxiang(Institute of Traditional Chinese Medicine and Materia Medica of Jilin Province, Changchun 130021);Analysis on Hydrolysates(Hypoxanthine and Adenine) in Alkaline Solution of Monoamine Oxidase From Liver Tissues of Mice by Reversed-phase Liguid Chromatography[J];Chinese Journal of Analytical Chemistry;1992-04
4 YANG Cui-cui;LI Lin;ZHANG Lan;Department of Pharmacology,Xuanwu Hospital of Capital Medical University,Key Laboratory for Neurodegenerative Diseases of Ministry of Education;;Evaluation of Alzheimer's Disease Animal Models[J];Journal of Chengdu Medical College;2013-04
5 LI Ting~1,LIU Jian-wen~(1),CAO Yan~1,ZHANG Xiao-dong~1,WEI Dong-zhi~2,LU Yan-hua~2(1.School of Pharmacy,East China University of Science and Technology,Shanghai 200237,China;2.State Key Laboratory of Bioreactor Engineering,East China University of Science and Technology);Neuroprotective Effect of Picrosides on Analog Dementia Model in Mice Induced by Galactose and Nitrite Natrium[J];Journal of East China University of Science and Technology(Natural Science Edition);2006-05
6 Li Jinglun, Xu Xiaowu,Liu Changzheng.Department of Neurology,the first affiliated hospital of Luzhou Medical College,Sichun 646000;Study of hoperbarlc oxygen combined with estradlol therapy on learning and memoryy disfunction in senile dementia rats[J];Henan Journal of Practical Neurons Diseases;2005-03
7 Hu Mei,Liu Qunliang,Zhang Yuejuan,et al(TCM Univ.of Hunan,Changsha,410007);Experimental Study on Effect of Huan Shao Dan on Monoamine Oxidase Activity in Rats[J];Journal of Hunan Traditional Chinese Medicine University of Hunan;2005-05
8 BIAN Ling1,CHEN Jun-xia1,PAN Lin-mei2,QIU Bi-han2,LI Huan2(1.Nanjing Maternal and Children Health Hospital,Nanjing 210029,China;2.Key Laboratory of Separation Engineering of Chinese Traditional Medicine Compound,Nanjing University of Chinese Medicine,Nanjing 210029,China);HPLC method for determination of uridine in low temperature grinding placenta[J];Practical Pharmacy and Clinical Remedies;2012-01
9 YANG Fan,ZHANG Hong,XU Jing(Geriatrics Department of Affiliated Gulou Hospital,Nanjing University of Chinese Medicine,Nanjing,Jiangsu,210008,China);Effect of Prescriptions for Reinforcing Kidney and Invigorating Spleen on Memory of Dementia Rat Model Induced by Ibotenic Acid[J];Journal of Nanjing University of Traditional Chinese Medicine;2008-06
10 LIU Chun-fu1 WANG Xiang-yang1 Zhang Yun-ling1 LINA3 1 hospital of Inner Mongolia TCM 010020;2 City hospital of Huhhaote 010010;3 Hospital of Traditional Chinese-Mongolia Medicine,Huhhaote 010010;The Experiment and investigation of QSZLP treating mice with AD[J];Nei Mongol Journal of Traditional Chinese Medicine;2013-01
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 HAN Guang-Xuan, WANG Li-Xin, ZHANG Wei-Dong, YANG Zhi, LI Ting-Zhao, JIANG Tao, LIU Wen-Yong (1.No. 534 Hospital of PLA,Luoyang 471003, China; 2. The Institute of Drug Inspection, Shenzhen 5l8029; 3. Department ofNatural Pharmaceutical Chemistry, College;Study on chemical constituents of Bletilla striata(I)[J];Academic Journal of Second Military Medical University;2002-04
2 HAN Guang-Xuan 1, WANG Li-Xin 2, ZHANG Wei-Dong 2, WANG Mai-Li 1, LIU Hong-Tao 1, XIAO Jian-Hua 1(1. No.534 Hospital of PLA, Luoyang 471003, China; 2. Department of Natural Pharmaceutical Chemistry, College of Pharmacy,Second Military Medical Univer;Studies on chemical constituents of Bletilla striata Ⅱ[J];Academic Journal of Second Military Medical University;2002-09
3 Sheng Yang HUANG2, Jian Gong SHI1*, Yong Chun YANG1, Shi Lin HU2 1Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Bejing 100050 2Institute of Chinese Materia Medica , Chinese Academy of Traditional Chine;Two New Isobutyltartrate Monoesters from Coeloglossum viride (L.) Hartm. var. bracteatum (Willd.) Richter[J];中国化学快报(英文版);2002-06
4 Sheng Yang HUANG2, Jian Gong SHI1*, Yong Chun YANG1, Peng Fei TU2 1Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050 2Department of Natural Medicines, School of Pharmaceutical Sciences, Peking University, Beijing 100083;Two New Tartrate Derivative Glucosides from Coeloglossum viride ( L.) Hartm. var. bracteatum ( Willd.) Richter[J];中国化学快报(英文版);2003-08
5 Gao lin~(1,2),Zhang boai~(1) Chen lieran~1,et al.1.Department of Neurology,The First Affiliated Hospital of Zhengzhou University,Zhengzhou,450052 2.The medical college of Henan Universify;Study the change of choline acetyltransferase and acetylcholinesterase activity in normal different age rat[J];Chinese Journal of Practical Neruous Diseases;2006-02
6 ZHANG Peng-wei1,Li Hai-long1,TAN Yin-feng1,SU Wen-qin1,ZHANG Jun-qing1,Fan Kai2,LIU Ming-sheng1(1.Hainan Medical University,Hainan Provincial Key Laboratory of R&D of Tropical Herbs,Haikou 571101,China;2.Tianjin Tasly Modren TCM Resources Co.Ltd,Tianjin 300402,China);Primary pharmacodynamics study on Bletilla Striata patchs[J];Journal of Hainan Medical University;2011-01
7 TAN Zhao-yang, YUAN Hong-jia,YOU Zhao-ling, Hunan University of Chinese Medicine, Changsha, China, 410208;Study on the Separation of Effective Components in Panax Notoginseng[J];Guiding Journal of Traditional Chinese Medicine and Pharmacy;2010-01
8 XIE Jing, ZHANG Hao*, YU Sen, CHEN Chu (West China School of Pharmacy, Sichuan University, Chengdu 610041, China);Pharmacognostic identification of original plants of Tibetan medicine “Shoushen”[J];West China Journal of Pharmaceutical Sciences;2005-03
9 ZHANG Shi yi, CHEN Yan, ZUO Ping ping, et al (Institute of Basic Medical Sciences, CAMS & PUMC, Beijing 100005, China);Therapeutic effect of 764-3 on rat with Alzheimer's like disease[J];Basic Medical Sciences and Clinics;2001-01
10 LU Bo~②,XU Ya-Min,ZHANG Han-Ming~③,LI Tie-Jun~③,QIU Yan~③ (~②Department of Pharmacy,411th Hospital of PLA,Shanghai 200081 China) (~③College of Pharmacy,The Second Military Medical University,Shanghai 200433 China);Effects of Different Extracts from Bletilla Colloid on Rabbit Platelet Aggregation[J];Pharmaceutical Journal of Chinese People's Liberation Army;2005-05
【Secondary References】
Chinese Journal Full-text Database 2 Hits
1 ZHOU Ya-nan,YANG Bin,DAI Jing-feng,QIN Xiao-yan*(College of Life & Environmental Science,Minzu University of China,Beijing 100081,China);Protective Effect of Coeloglossum viride var. bracteatum Extract against Injury Induced by Amyloid Peptide in Rat Prefrontal Cortex Neurons[J];Lishizhen Medicine and Materia Medica Research;2011-05
2 WANG Xin 1 ,LI Jing 2 ,LIAO Yi-lan 1 ,DENG Chun-lan 1 (1.Dept. of Pharmacy,Chonggang General Hospital,Chongqing 400080,China;2. Dept. of Pharmacy,Chongqing Three Gorges Medical College,Chongqing 404120, China);Study on Protective Effect of Water Extract from Morindae officinalis on Alzheimer Disease Model Rats[J];China Pharmacy;2013-31
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