Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《China Pharmacist》 2002-05
Add to Favorite Get Latest Update

Synthesis of Zaleplon

Huang Xuefeng, Li Yuyan, You Qidong (Dept. of Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, P. R. China)  
Objective: To research the synthesis technique of zaleplon. Method:Zaleplon was prepared from acetophenone by nitrating, reducting, acetylating, condensation with dimethy formide dimethylacetal, alkylation with ethyl iodide and cyclization with 3-aminopyrazole-4-carbonitrile,ets. Conclusion; This synthetic route is reasonable, the total yields of zaleplon was 3.2% .
【CateGory Index】: R914
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 1 Hits
1 CAI Zhao-sheng~1,YANG Chun-sheng~1,WANG Jin-tang~2 (1.Department of Chemical and Biological Engineering,Yancheng Institute of Technology,Yancheng 224003,Jiangsu,China;2.School of Science,Nanjing University of Technology,Nanjing 210009,Jiangsu,China);An Improved Way to Prepare m-Nitroacetophenone[J];Fine Chemicals;2006-11
Chinese Journal Full-text Database 3 Hits
1 Liu Jianning (Department of Chemistry,Qingyang Teacher′s College,Xifeng 745000) Zhao Jianshe Ren Youxian (Department of Chemistry,Northwesst University,Xian 710069);SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF Cu,Zn,Co,Ni COMPLEXES OF 3 NITROACETOPHENONE THIOSEMICARBAZONE Ⅰ[J];CHEMICAL RESEARCH AND APPLICATION;1997-04
2 Hong Zongguo Chen Donghua Zhang Aiqing Deng Kejian Du Chengzhi(College of life science and chemistry, South-Central University for Nationalities, Wuhan 430074);Synthesis of Photosensitive polyimide precursor Dinitrochalcone[J];Chinese Journal of Colloid and Polymer;2003-03
3 LIU Jian Ning\ YU Xing Qiao\ DONG Yan Jie (Department of Chemistry, Qingyang Teacher′s College, Xifeng 745000) SHI Qi Zhen (Department of Chemistry, Northwest University, Xi′an 710069);THE DIRECT ELECTROCHEMICAL SYNTHESIS OF Cu(Ⅰ), Zn(Ⅱ), Fe(Ⅱ) Sn(Ⅱ), Pb(Ⅱ) COMPLEXES OF 1,5 Bis(3 NITROACETOPHENONE) THIOCARBOHYDRAZONE[J];CHINESE JOURNAL OF INORGANIC CHEMISTRY;1999-05
【Secondary References】
Chinese Journal Full-text Database 1 Hits
1 YU Jiang-jiang,LIANG Qu,LI Hao(College of Materials,Chemistry and Chemical Engineering,Chengdu University of Technology,Sichuan Chengdu 610059,China);The Laboratory Synthesis and Structure Characterization of 3'-Nitropropiophenone[J];Guangzhou Chemical Industry;2010-01
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved