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《Information on Traditional Chinese Medicine》 2010-03
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The Inhibted Effect of Chlorogenic Acid from the Honeysuckle on Virus in Vitro

HU Ke -jie,WANG Yue -hong,WANG Dong (The Second Affiliated Hospital of Harbin Medical University,Harbin 150086,China)  
Objective:To study the effect on virus inhibition by Chlorogenic acid in vitro. Methods:Utilizing the culture hep-2 cell and the mixed experiment to observe the inhibited effect of Chlorogenic acid on virus of commonly seen in respiratory tract infection. Results:The concentration of Chlorogenic acid separately being 0. 05mg/mL、0. 1mg/mL、0. 4mg/mL、0. 8mg/mL,could separately inhibite Respiratory Syncytia Virus、Cox-sackie B3 virus、Adeno-Associated 7 virus、Adeno-Associated 3 virus and Coxsackie B5 virus. Conclusion:Chlorogenic acid has a strong inhibited effect on virus of commonly seen in respiratory tract infection.
【Fund】: 国家1035工程课题(969010114)
【CateGory Index】: R285.5
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【Citations】
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【Co-citations】
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1 WANG Li-chuan (Department of Bio-chemistry,Xingtai University,Xingtai,Hebei 054001);Research Progress on Chemical Compositions and Efficacy of Lonicera spp.[J];Journal of Anhui Agricultural Sciences;2009-05
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6 FENG Gan-zhu1,ZHOU Feng2,HUANG Mao3,YAO Kun21Department of Respiratory Medicine,Second Affiliated Hospital of Nanjing Medical University,Nanjing 210011;2Department of Microology and immunology,Nanjing Medical University,Nanjing 210029;3Department of Respiratory Medicine,First Affiliated Hospital of Nanjing Medical University,Nanjing 210000,China;Inhibitory effects of Reduning injection on human rhinoviruses in vitro[J];Journal of China Pharmaceutical University;2008-03
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