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《Chinese Journal of Medical Imaging Technology》 2008-01
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Experimental study of implanted microwave ablation in vivo porcine kidney

ZHANG Da-kun~1 DONG Bao-wei~(2*)ZHANG Xin-li~1 LIANG Ping~2 YU Xiao-ling~2 WANG Yang~2 LI Meng~1 (1.Department of Ultrasound,the 302 Hospital of PLA,Beijing 100039,China; 2.Department of Ultrasound,the PLA General Hospital,Beijing 100853,China)  
Objective To investigate the ablation effects of implanted microwave on vivo porcine kidney and provide experi- mental foundation for microwave ablation renal tumor.Methods The rigid implanted microwave antenna with internally wa- ter-cooled was directly implanted into porcine kidney parencbyma in vivo.Microwave frequency was 2450 MHz.The energy output was 50-80 W/600 s.Ablations were performed in differential irradiation powers and time.Results The shapes of ablation lesions were all elliptical.The central area was composed of charred and ablated region.Histological examination re- vealed complete coagulation necrosis in this area.Beyond this ablation area,hemorrhaging was scattered,and renal tubules were dilated in congestive region.In the circumferential region,the renal parenehyma showed a morphologically normal find- ing.The ablation volume,maximum longitudinal,transverse diameters of ablation lesions and the temperature change around the microwave antenna were analyzed.Conclusion The rigid implanted microwave antenna can produce reproducible elliptical ablation lesion in shape.This research provides technical foundation for the clinical application of the microwave ab- lation renal tumor.
【CateGory Index】: R737.11
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