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《Chinese Journal of Medical Imaging Technology》 2008-07
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fMRI study of acupuncture at adjacent acupoints located on the Stomach Meridian of Foot-Yangming

LI Lin1,2 , XU Jian-yang3, LI Yong-zhong4, LIU Hua 1, YUAN Xiu-li1, LI Kun-cheng4, SHAN Bao-ci1(1.Key Laboratory of Nuclear Analysis Techniques, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China; 2.Graduate School of Chinese Academy of Sciences, Beijing 100049, China; 3.Department of Integrated Traditional Chinese and Western Medicine, General Hospital of Chinese People’s Armed Police Forces, Beijing 100039, China; 4.Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China)  
Objective To investigate the fMRI signal changes in the human brain induced by acupuncture at adjacent acupoints located on the Stomach Meridian of Foot-Yangming. Methods Twenty-seven healthy right-handed subjects were divided into three groups randomly and received acupuncture at right ST43 (Xiangu), right ST44 (Neiting) and their nearby sham acupoint respectively. Brain functional images of all subjects were obtained during acupuncture stimulation. Through analysis fMRI data from all subjects using SPM2 software, the activation patterns in central nervous system (CNS) evoked by acupuncture were acquired. Results The results showed that two acupoints under consideration had the common effect of activating three specific areas of the brain: the bilateral SI/MI, the ipsilateral cerebellum and SII. Acupuncture at ST43 specifically activated ipsilateral medial frontal gyrus, inferior frontal gyrus, ACC and thalamus. Stimulation of ST44 selectively activated bilateral PCC, contralateral middle frontal gyrus, inferior frontal gyrus, precuneus, and ipsilateral lingual gyrus, middle occipital gyrus, lentiform nucleus. Conclusion This phenomenon validated that acupuncture at adjacent same-meridian acupoints, which had similar clinical functions, would activate specific responses in CNS, which were relevant to the therapeutic effects of the acupoints.
【Fund】: 国家自然科学基金项目(30570508)
【CateGory Index】: R245.9
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1 LU Yan;SUN Ying-xia;YU Xiao-hua;ZHANG Jing;SUN Zhao;LI Jin-ling;ZHANG Xi-peng;WANG Tong;WANG Shi-jun;College of Acumox and Tuina,Shandong University of TCM;College of Basic Medical Science,Shandong University of TCM;Nursing School,Shandong University of TCM;International Education College,Shandong University of TCM;;Effects of Electroacupuncture on “Taichong” and “Tianshu” on Levels of 5-HT, NE and CGRP in Rats with Diarrhea Type Irritable Bowel Syndrome[J];中国中医药信息杂志;2015-10
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