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《Chinese Journal of Medical Imaging Technology》 2008-07
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Left ventricular systolic function assessed by two-dimensional speckle tracking imaging in patients with type 2 diabetes mellitus

MA Hong, XIE Ming-xing, HU Li-jun, WANG Jing, WANG Xin-fang, LV Qing, LU Xiao-fang, YANG Ya-li(Department of Ultrasound, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology; Hubei Provincial Key Laboratory of Molecular Imaging, Wuhan 430022, China)  
Objective This study investigated the long-axis global and regional systolic function of the left ventricle (LV) in patients with type 2 diabetes mellitus (T2DM) using two-dimensional speckle tracking imaging (STI). Methods STI was performed in 103 subjects with normal ejection fraction: 41 with diabetes mellitus only (DM group), 25 with both diabetes and left ventricular hypertrophy (DH group), and 37 normal controls. Longitudinal peak systolic strain of six walls in apical long-axis, four-chamber, and two-chamber views was measured, and average peak strain in the long axis at basal, middle and apical levels, and LV global peak strain were assessed. Results Peak strain of each plane in all patients (DM, DH) was significantly reduced when compared with controls(P0.01), and peak strain of basal and middle segments in DH group was lower than in DM group (P0.05). All patients showed significantly reduced average peak strain in the long axis at basal, middle and apical levels, and global peak strain compared with controls (P0.001), and DH group was significantly lower than DM group (P0.01). Conclusion STI may be used to identify early abnormalities in patients with T2DM who have normal left ventricular systolic function.
【CateGory Index】: R445.1;R587.1
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