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《Chinese Journal of Medical Imaging Technology》 2010-01
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Diagnosis of small single solid thyroid nodule with real-time ultrasound elastography

DAN Hai-jun 1,WANG Yan 2,DAN Hai-yong 3,LU Bao-jin 4,LI Tao 1,HU Bing 2(1.Department of Ultrasound,3.Department of Hematology,4.Physical Examination Center,the Second Hospital of Hebei Medical University,Shijiazhuang 050000,China;2.Department of Ultrasound in Medicine,Shanghai Jiao Tong University Affiliated Sixth People's Hospital,Shanghai 200233,China)  
Objective To assess the diagnostic value of ultrasonographic elastography for identifying suspected malignant thyroid nodules.Methods Fifty-one patients with small single solid thyroid nodule underwent two-dimensional and color power Doppler ultrasonography.The size,shape,boundary,internal echo and halo,calcification of thyroid nodule were observed with two-dimensional ultrasound.Then color Doppler ultrasonography was used to detect blood signal and distribution in the nodules.Longitudinal scanning of elastography was performed,and the findings on elastography were classified into Ⅰ-Ⅴ grades.The ultrasonographic results were compared with pathologic findings.Results Six patients were found with grade Ⅰ and Ⅱ benign lesions;9 with grade Ⅲ(6 benign and 3 malignant),36 with Ⅳ and Ⅴ(2 benign and 34 malignant)lesions on ultrasonographic elastography.Taking the elasticity grade Ⅳ or Ⅴ as malignant standard,the diagnostic sensitivity was 91.89%,specificity was 85.71%,accuracy was 90.20%,while the positive and negative predictive value was 94.44% and 80.00%,respectively.Conclusion Real-time ultrasound elastography is a promising imaging technique that can assist in the differential diagnosis of malignant thyroid small single solid nodule.
【CateGory Index】: R445.1;R581
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