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《Chinese Journal of Medical Imaging Technology》 2010-08
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Value of MR diffusion weighted imaging in diagnosis and staging of uterine cervical cancer

ZHAO Hai1,XIAO Xin-lan2*,GAO Ming-yong1,LU Rui-liang1,TAN Xiang-ping1(1.MR Room,Foshan Hospital of Sun Yat-Sen University,Foshan 528000,Chnia;MR Room,the Second Affiliated Hospital to Nanchang University,Nanchang 330006,China)  
Objective To investigate the sensitivity of detection and accuracy of staging in uterine cervical cancer(UCC) with MR diffusion weighted imaging(DWI) and apparent diffusion coefficient(ADC) value.Methods Totally 67 UCC patients confirmed pathologically(UCC group) and 20 healthy female subjects(control group) underwent routine pelvic MRI sequences and DWI.ADC values of normal uterine cervix(cervical endometrial,junctional zone and myometrium) and cervical carcinoma were compared.Results All patients were detected using DWI with routine MRI sequences.With only routine MRI sequences,64 cases were detected,while 3 cases were missed diagnosed.No difference was found between these two methods in staging of UUC.In control group,the average ADC value of three-layer structure of normal cervix was as follows: ADC of cervical endometrial was(1.54±0.15)×10-3 mm2/s,of junctional zone was(1.56±0.16)×10-3 mm2/s,while or myometrium was(1.81±0.16)×10-3 mm2/s.There was no significant difference between cervical endometrial and junctional zone,while the difference was found between myometrium with cervical endometrial and junctional zone.The average ADC value of cervical endometrial in UCC group was(1.05±0.20)×10-3 mm2/s,and there was statistically significant difference between UCC and normal cervical endometrial.Conclusion UCCs can be detected more sensitively with DWI combined with routine MRI sequences than only with routine MRI sequences.DWI has great clinical significance in distinguishing cervical carcinoma from normal uterine.
【CateGory Index】: R445.2
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