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Diagnosis of cerebrovascular diseases with 128-detector CT

HE Wen-juan,SHEN Jia-lin,XU Jian-rong,HUA Xiao-lan(Department of Radiology,Renji Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200127,China)  
Objective To explore the value of whole-brain perfusion with 128-detector computed tomography(CT) in ischemic cerebrovascular diseases.Methods Fourty patients dignosed as ischemic cerebrovascular diseases underwent plain CT and CT perfusion(CTP) within 24 h after the onset of symtoms.Follow-up MR DWI were performed in 24—72 h after the onset of symtoms.Results Among the 40 patients,20 lesions were detected with plain CT in 17 patients,and 42 lesions were detected with CTP.Among the 22 lesions missed in plain CT,reduced CBF,CBV and prolonged MTT,TTP were showed in 15 lesions,while CBF reduced and CBV prolonged in 4 lesions,MTT and TTP prolonged or no change in CBF and CBV in 3 lesions.Follow-up MR DWI confirmed that 35 lesions in which CBF and CBV reduced together developed to infarct foci.Conclusion Within 24 h after the onset of symtoms,whole-brain perfusion with 128-slice CT could increase the detectable rate of the ischemic lesions significantly,therefore has important value in early detection of ischemic lesions and avoiding omission of lesions.
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