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《Chinese Journal of Medical Imaging Technology》 2011-08
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Assessment of coronary artery stenosis with dual-source CT angiography

ZHANG Yan-yan,FENG Bo,LI Pei-ling,XIE Xiu-li,REN Ling(Department of Radiology,the First Hospital of China Medical University,Shenyang 110001,China)  
Objective To observe the value of dual-source CT angiography(DSCTA) in assessing coronary artery stenosis.Methods DSCTA and CAG data of 41 patients with suspected or definitely diagnosed coronary heart disease were retrospectively analyzed.Taking CAG results as the gold standard,the sensitivity,specificity,positive predictive value,negative predictive value and accuracy in diagnosing mild grade stenosis(stenosis of lumen 50%),medium grade stenosis(lumen stenosis 50%-75%),severe grade stenosis(stenosis of lumen ≥75%) as well as the above indices of general stenosis were calculated.Results Among the 546 coronary artery segments(the diameter ≥1.5 mm) of 41 cases,535 segments were satisfied with diagnostic requirements,while the other 11 segments were impossible to assess because of the calcified plaques masking the artery vessel.The diagnostic sensitivity,specificity,positive predictive value,negative predictive value and accuracy of DSCTA for mild grade stenosis was 69.23%(36/52),96.60%(341/353),75.00%(36/48),95.52%(341/357) and 93.09%(377/405),for medium grade stenosis was 68.42%(26/38),99.42%(341/343),92.86%(26/28),96.60%(341/353) and 96.33%(367/381),for severe grade stenosis was 70.67%(53/75),99.71%(341/342),98.15%(53/54),93.94%(341/363) and 94.48%(394/417),while for the general stenosis was 64.61%(115/178),95.52%(341/357),87.79%(115/131),84.41%(341/404) and 85.23%(456/535),respectively.Conclusion As a noninvasive method of inspection,DSCTA can provide high accuracy in detecting coronary artery stenosis.
【CateGory Index】: R816.2
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