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《Chinese Journal of Birth Health & Heredity》 1993-01
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Jin Fan et al (Affiliated Obstetrics and Gynecology Hospital, Zhejiang Medical University, Hangzhou) (310006)  
Study of changes in maternal serum AFP (MSAFP) level before and after chorionic villus sampling (CVS) showed that MSAFP level was significantly increased after CVS (t=2.44, P0.05) . The means of elevated concentration and percentage ofMSAFP were 44.l3±18.12ng/ml and 419.91 ±195.54%(M±SE)respectively. Analyses of linear correlation showed that the elevated percentage of MSAFP had no significant correlation to gestation and the number of passage of the catheter but significant positive correlation to the size of obtained tissue (r=0.59, p0.01) . These results suggested that under the current condition in our country fetomaternal bleeding (FMB) also occurs during the procedure of CVS and the amount of FMB is probably associated with the size of obtained tissue.
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