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《Chinese Journal of Birth Health & Heredity》 2011-01
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Results analysis of detecting chlaydia trachomatis and ureaplasma urealyticum in patients with missed abortion by fluorescent quantitative PCR

GENG Yao,NIU Cheng-ling,WANG Feng-yu.(Department of Genetics,Research Institute of Population and Family Planning in Henan Province,Zhengzhou,Henan,450002)  
Objective: To investigate the correlation between the infections of Chlaydia Trachomatis (CT) and Ureaplasma Urealyticum (UU) and the occurrence of the missed abortion in pregnant women,and discuss the meaning of diagnosis missed abortion using fluorescent quantitative PCR (FQ-PCR).Methods: Detecting content of CT-DNA and UU-DNA in missed abortion patients' cervical secretions by FQ-PCR.Results: There are 72 patients infected by CT or UU in all of 138 cases with missed abortion.The total detection rate is 53.62% ,of which CT-positve rate is 21.74% ,UU-positve rate is 42.03% ,and mixed infection is 10.14%.The results are statistically significant differences with the normal population controls (P 0.05).Conclution: Infections of CT and UU in genitalduct are closely related with missed abortion,and detection of CT and UU in patients with missed abortion by FQ-PCR is simple,fast and accurate.
【CateGory Index】: R440;R714.2
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