Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chinese Journal of Birth Health & Heredity》 2011-01
Add to Favorite Get Latest Update

Analysis on the result of 13600 pregnant women's serum triple screening test for fetal Down syndrome in second-tri-mester

TANG Hui-jing,FENG Xiao-chun,LUAN Hai-ping,YANG Su-xia.(Putuo Materal and Children Health Hospital,Shanghai,200060,China)  
Objective: To explore the relationship between the pregnant women's serum triple screening test in second-trimester and detection rate of picking out fetal Down syndrome.Method: Underwent triple screening test (alpha fetoprotein,AFP;human chorionic gonadotrophin,HCG and unconjugated estriol,uE3) by chemiluminescent immunoassay in second-trimester (15-20 weeks).using the specialized software calculated the risk of Down's.The suggestion carried on which the result bigger than 1: 380 is positive analyzing the chromosome nuclear type of the amniotic fluid.Resluts: 1281 examples screening is positive among 13600 pregnant women.In the pregnant women who volunteer to accept the amniotic fluid examination,picked out 6 examples of fetal Down syndrome,and also picked out 18 trisomy syndrome 4 examples,other unusual chromosome 6 examples.Conclusion: The pregnant women's serum triple screening test in second-trimester takes effect in screening the fetal birth defect,especially in screening trisomy syndrome.To reduce the flaw birth,the pregnant woman screening result assumes high-risk should carry on analyzing the chromosome nuclear type of the amniotic fluid.
【CateGory Index】: R714.55
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 6 Hits
1 Li Long;He Jianfeng;Zhu Baosheng;Teaching Management Office,The Second Affiliated Hospital of Kunming Medical University;Department of Biomedical Engineering,Kunming University of Science and Technology;Genetic Diagnosis Center,The First People's Hospital of Yunnan Province;;Triple serum tests screening for Down's syndrome in women at second trimester:a meta analysis[J];中华围产医学杂志;2016-02
2 WU Chun-mei;YIN Li-li;LI Xia-lian;Clinical Laboratory,the 264 PLA Hospital in Taiyuan;;The Screening Result of Down's Syndrome in Pregnant Woman with Mid-gestation[J];标记免疫分析与临床;2013-05
3 FENG Zong - hui;Huaihua Maternal and Child Health Care Hosptial;;Analysis of 91 cases of abnormal karyotype of chromosome in prenatal diagnosis in Huaihua are[J];中国优生与遗传杂志;2013-09
4 WU Xing-fei1,SHI Xin-wei2,ZHAO Lan1,DUAN Xiu-juan2,CUI Tian-pen1,CHEN Xing,HU Bi-Cheng,QIAO Fu-yuan2.(1.Department of Clinical Laboratory,Wuhan First Hospital,Wuhan,China,430022;2.Department of Obstetrics and Gynecology,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,Hubei 430030,China);Analysis on results of Down's syndrome screening in 2046 pregnant women in second trimester in Wuhan[J];中国优生与遗传杂志;2013-08
5 FU Han-dong*,LU Min,WEI Wei,YU Hong,YU Xiao-yan,ZHENG Shu-ping(*Central Laboratory,Xiaogan Central Hospital,Xiaogan 432000,China);Application analysis of Down syndrome screening for prenatal diagnosis in Xiaogan[J];中华实用诊断与治疗杂志;2013-08
6 LI Yi.(Department of Reproduction and Genetics in the Central Hospital of Tai'an,271000);Analysis of antenatal screening and antenatal diagnosis of 18 593 cases in Tai'an[J];中国优生与遗传杂志;2013-04
Chinese Journal Full-text Database 10 Hits
1 ZHOU Qian;HU Xiao-yu;JIANG Yu-lin;BIAN Xu-ming;LIU Jun-tao;Department of Obstetrics and Gynecology,Peking Union Hospital,Chinese Academy of Medical Sciences & Peking Union Medical College;;Maternal serum markers for Down syndrome screening in second-trimester and its relations with adverse pregnant outcomes[J];中华围产医学杂志;2013-09
2 YANG Fang 1,2,$ , WANG Hua 3,$ , SHI Jing Cheng 1,# , and HU Ming 1,# 1. Department of Epidemiology and Biostatistics, School of Public Health, Central South University, Changsha 410078, Hunan, China; 2. Department of Molecular Biology, School of Bioscience and Technology, Central South University, Changsha 410078, Hunan, China; 3. Center of Prenatal diagnosis, Maternal and Child Health Hospital of Hunan Province, Changsha 410008, Hunan, China;Validity of Different Methods to Prenatal Screening for Down’s Syndrom During First and Second Trimester Pregnancy of Chinese Women[J];Biomedical and Environmental Sciences;2013-02
3 YU Dong-yi,WANG Fang,LIU Qi,JIANG Nan,ZHAO Wei,REN Hui-ying,HAN Mei-yan,ZHANG Kai,LI Shuo,OUYANG Qi-qi,NIEQun.(Department of Genetics,Qingdao Maternal and Children's Hospital,Qingdao,Shandong 266034,P.R.China);Establishment and application of median serum markers for second trimester screening in Qingdao region[J];中华医学遗传学杂志;2012-05
4 YUAN Hui1,WANG Hong2,LUO Fu-wei2,OUYANG Shu-yuan2,WU Xiao-xia1,WANG Chen-hong1.(1.Department of Obstetrics,2.Department of Clinical Laboratory,Shenzhen Maternity and Child Healthcare Hospital Affiliated to Southern Medical University,Shenzhen,518028,China);Clinical analysis of Down′s syndrome screening:44 147 pregnancies in Shenzhen[J];中国优生与遗传杂志;2012-05
5 FU Han-Dong,LU Min,YANG Shu-Jie,XIA Yao-Zong,WU Jian-Wen.Department of Child Health Care,Xiaogan Maternal and Children′s Health Care Hospital,Xiaogan,Hubei 432000,China;Causes of neonatal death in the Xiaogan region of Hubei Province between 2007 and 2010[J];中国当代儿科杂志;2012-03
6 HE Gui-er,WANG Yun-duan,HUANG shuang,WANG Jing-jing,HUANG Zhi-cheng.Department of Clinical Laboratory,Guangzhou Panyu He Xian Memorial Hospital,Guangzhou 511400,China;Screening results analysis on Down syndrome in 13736 case of middle period pregnancy[J];国际医药卫生导报;2012-02
7 LIANG Hong,GAO Lan,CHEN Ying. Maternity and Child Healthcare Hospital of Chengdu,Chengdu 610031,Sichuan Province,China.;Investigation on Reasons of Refusing Amniocentesis by High-risk Pregnant Women With Down's Syndrome[J];预防医学情报杂志;2011-09
8 JIANG Tao,SUN Yi-jun,XU Qian-jun,SUN Yun,ZHANG Xiao-juan,CAO Li,ZHA Wen,ZHANG Jin,HUANG Mei-lian,CHEN Chun-hua,LIN Yuan-shan,XU Zheng-feng. Prenatal Diagnosis Center,Nanjing Maternal and Child Health Hospital Affiliated to Nanjing Medical University,Nanjing 210004,China;Results of second-trimester prenatal screening using two serum markers for Down's syndrome in 60 931 pregnant women[J];中华围产医学杂志;2011-02
9 TANG Hui-jing,FENG Xiao-chun,LUAN Hai-ping,YANG Su-xia.(Putuo Materal and Children Health Hospital,Shanghai,200060,China);Analysis on the result of 13600 pregnant women's serum triple screening test for fetal Down syndrome in second-tri-mester[J];中国优生与遗传杂志;2011-01
10 QIN Ting,TIAN Mao,MO Wei-ying,SHI Yue-qiu.(People's Hospital of Guangxi Zhuang Autonomous Region,530021);The prognosis analysis on the 32 cases with chromosome abnormality among 1075 cases in prenatal diagnosis[J];中国优生与遗传杂志;2011-01
【Secondary References】
Chinese Journal Full-text Database 4 Hits
1 LI Li;MING Yan;YE Ping;Department of Gynecology and Obstetrics,the First People's Hospital of Xiaoshan District;;Relationship between fetal intrauterine growth restriction and serum levels of human chorionic gonadotropin and placental isoferritin[J];中国妇幼保健;2014-27
2 ZHU Hui-chao;ZHU Wen-biao;HE Xiao-shan;Meizhou People's Hospital;;Clinical Applications of Second Trimester Screening for Down in Prenatal Diagnosis[J];现代诊断与治疗;2014-16
3 YU Ru-kui;CHEN Ai-e;CHEN Na-bo;Department of Women Health Care,Yuyao Institute of Maternal and Child Care;;Results analysis and clinical significance on prenatal screening of 1188 cases of early and mid pregnancy integration[J];中华全科医学;2014-04
4 LIU Li-Hua;LU Xiao-Qing;LIU Cong-Hui;Department of Pathophysiology,School of Basic Medicine,He-bei United University;;Analysis on the correlation between pregnant women's age and prenatal screening of Down's syndrome in pregnant metaphase[J];中国妇幼保健;2014-08
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved