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WT5BZ]Huang Suizhu 黄遂柱, Zhao Yongqiang 赵永强, and Shangguan Feng 上官峰 [WT5”BX]Peoples Hospital of Henan Province, Zhengzhou 450003 [WT5”BZ]  
Closed right middle femoral fractures were made with fracture apparatus in balb/c mice in whom a significant bone loss had appeared 3 mouths after ovariectomy and treated by different doses of estrin. Then the callus specimens were treated and harvested in batches and examined histologically. From the results it was found that little callus was formed in the mice not treated by estrin after ovariectomy, while the callus development was significantly delayed in the mice treated by a high dose of estrin, suggesting that the supplement of an ultra physiological dose of estrin was harmful to the early fracture healing in ovariectomized mice.
【CateGory Index】: R683
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