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《THE JOURNAL OF TRADITIONAL CHINESE ORTHOPEDICS AND TRAUMATOLOGY》 2000-01
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THE INFLUENCE OF TRADITIONAL CHINESE DRUGS ON THE METABOLISM OF OXYGEN FREE RADICAL IN EXPERIMENTAL RABBIT KNEE OSTEOARTHRITIS

WT5BZ]Ma Jianbing 马建兵, Liu Deyu 刘德玉, Li Kanyin 李堪印, et al [WT5”BX]Red Cross Society Hospital of Xi an City, Shaanxi Province, Xi an 710054 [WT5”BZ]  
In order to explore the influence of traditional Chinese drugs (TCD) on the metabolism of oxygen free radical in osteoarthritis, rabbit models of knee osteoarthritis were made by Hulths method and randomly divided into three groups: Groups Ⅰ, Ⅱ and Ⅲ, which were treated by nothing, Fenbid and “ZHUYU TANG” (ZYT, TCD Decoction Activating Blood Flow and Removing Blood Stasis), respectively. One month after the treatment, the erythrocytic SOD activities and the plasma LPO levels of the three groups were measured and statistically analysed. The results showed that the SOD activity of Group Ⅲ was much higher , while the LPO level was much lower, than those of the other two groups (P 0.01) and there was no significant difference between Group Ⅰ and Group Ⅱ (P 0.05). It was considered that ZYT functions to improve SOD activity and to lower LPO level significantly and thus to delay the degeneration of joint cartilage and to accelerate the cartilage repair.
【CateGory Index】: R285
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