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《THE JOURNAL OF TRADITIONAL CHINESE ORTHOPEDICS AND TRAUMATOLOGY》 2000-06
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THE TREATMENT OF RABBIT OSTEOARTHRITIS OF THE KNEE BY KIDNEY REINFORCING AND BLOOD CIRCULATION ACTIVATING METHODS: A Comparative Study of Pathomorphology

WT5BZ] Gao Wenxiang 高文香, Ren Hanyang 任汉阳, Zhou Ying 周 颖, et al  
Luoyang Orthopedic Traumatologica Hospital and Institute of Henan Province, Luoyang 471002 [WT5”BZ]Rabbit models of osteoarthritis were made by injecting papain into rabbit knees and treated by transgastrically given kidneys reinforcing (KR) and blood circulation activating (BCA) traditional Chinese drugs, respectively, and the influence of the KR and BCA drugs on the cartilage and synovium of the models were observed as to explore whether the therapeutic effects of KR and BCA methods are related to the onset time of osteoarthritis or not. Six and ten weeks after the modelling, the specimens were taken and observed by optical and transmission electron microscopes. The results showed a lower synovium injury severity in BCA group 6 weeks after the modelling than that in KR group (P 0.05) and a milder cartilage destruction in KR group 10 weeks after the modelling than that of BCA group (P 0.05). From this it can be seen that BCA drugs have a better therapeutic effect at the early stage of osteoarthritis, while KR drugs have an advantage in the therapeutic effect with progress of the disease course.
【CateGory Index】: R274
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