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《The Journal of Traditional Chinese Orthopedics and Traumatology》 2015-01
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Clinical study on acupuncture therapy combined with oral application of Guli Jiaonang(骨力胶囊) for treatment of knee osteoarthritis

TAN Fuzhu;ZHANG Lexin;REN Shujun;The First Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine;Heilongjiang University of Traditional Chinese Medicine;  
Objective: To observe the clinical curative effects of acupuncture therapy combined with oral application of Guli Jiaonang( 骨力胶囊,GLJN) for treatment of knee osteoarthritis( KOA). Methods: Sixty patients with KOA were randomly divided into 3 groups,20 cases in each group. The patients were treated with acupuncture therapy( acupuncture group),oral application of GLJN( GLJN group) and acupuncture therapy combined with oral application of GLJN( Combination group) respectively. Knee function scores were recorded and compared between the 3 groups before treatment and after one course of treatment respectively,and the clinical curative effects were evaluated and compared between the 3 groups after one course of treatment. Results: There was no statistical difference in knee function scores between the 3 groups before treatment( 20. 63 + /- 0. 94,20. 60 + /- 1. 99,19. 64 + /- 2. 08 points,F = 1. 395,P = 0. 459). There was statistical difference in knee function scores between the 3 groups after one course of treatment( 28. 67 + /- 1. 31,32. 08 + /- 0. 98,33. 01 + /- 2. 04 points,F = 18. 637,P = 0. 008). Further pairwise comparison showed that the knee function score of combination group was higher than that of acupuncture group and GLJN group( P = 0. 002,P = 0. 001). There was no statistical difference between acupuncture group and GLJN group( P = 0. 157). The KOA of 2 patients were controlled,4 good,10 fair and 4 poor in acupuncture group; 3 patients got good result,8 fair and 9 poor in the GLJN group; while the KOA of 3 patients were controlled,5 good and 12 fair in combination group. The clinical curative effect was better in combination group compared with the other 2 groups( Rcombination group= 22. 82,Racupuncture group= 29. 65,RGLJN group= 39. 02;χ2= 0. 129,P = 0. 006). Conclusion: The therapy of acupuncture therapy combined with oral application of GLJN can obviously improve the function of knee in patients with KOA,and it surpasses the monotherapy of acupuncture therapy and oral application of GLJN in curative effect,so it is worthy of popularizing in clinic.
【CateGory Index】: R274.9
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