Relations between Syndrome-typing in TCM and the Levels of PGE_2 and PGF_(2α) in Blood and Urine in Diseases of Stomach and Duodenum
Jin Jingshan, Zhao Ronglai, Wei Beihai, et al Beijing Institute of Traditional Chinese Med., Beijing, 100010, PRC.
In patients of deficient spleen, the blood PGE_2 is markedly elevated, whereas PGF_(2α), markedly lowered. That of urine PGE_2 and PGE_2/PGF_(2α)markedly increased. In deficient spleen treated with"Jianpi Yiqi"(Spleenstrenthening and Oi-benefit)Syrup and Disharmony of Liver and Stomach treated with"Qizhi Weiteng"(Stagnant Qi and Stomachache)Powder, there were no obvious changes in PGE_2 and PGF_(2α)before and after treatment. Comparison of the PG contents between patients of deficient Spleen and experi mental deficient Spleen rats revealed PGF_(2α), lowering in both groups, while FGE_2 increased in patients and lowered in rats, suggesting that there are differences as well as similarities in both grou(?)s, and this corresponds to the TCM assessment of animal models.