Comparative Study on Ultramicrostructures and Functions of the Thyroid in Rats of Excess-Heat Type and Deficiency-Heat Type
Xu Zhiwei, Chen Qun, Liu Yamei, College of Basical Medicine, Guangzhou University of TCM, Guangzhou 510405
Serum contents of triiodothyronine (T3), tetraiodothyronine (T4), reverse triiodothyronine (rT3) and thyroid - stimulating hormone (TSH) and changes of structures of the thyroid gland in the rat of exces - heat syndrome and deficiency - heat syndrome were observed with radioimmunoassay and electron microscopic technique, respectively. The rats of excess - heat syndrome and deficiency - heat syndrome were established with administration of Chinese herbs. Results indicated that serum T3 and T4 levels increased and the rT3 level tended to decrease in the deficiency - heat group, and thyroid follicle epithelial cell had more significant changes as compared with that of the excess - heat group. It is suggested that changes of hormones and ultra - microstructures of the thyroid can be served as an important basis for heat syndrome of deficincy type and excess type.