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Acta Pharmaceutica Sinica
FQ: 月刊
AD of Publication: 北京市
Lanuage: 中文;
ISSN: 0513-4870
CN: 11-2163/R
YP: 1953
Url: 中国药学会
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Acta Pharmaceutica Sinica
2008 -09
Synthesis and antinociceptive activity of seselin derivatives GUO Huan-fang,ZHOU Pei-lan,GONG Ze-hui,XIE Lan(Beijing Institute of Pharmacology and Toxicology,Beijing 100850,China)
A new norditerpenoid alkaloid from Aconitum taipaicum HE Yang-qing~1,MA Zhan-ying~2,YANG Qian~1,YAO Bing-hua~1,GAO Li-ming~3(1.Department of Applied Chemistry,Xi'an University of Technology,Xi'an 710054,China;2.Department of Chemistry,Xianyang Normal University,Xianyang 712000,China;3.Key Laboratory of Polymer Materials of Gansu Province,Northwest Normal University,Lanzhou 730070,China)
Three new xanthones from Garcinia xanthochymus ZHONG Fang-fang,CHEN Yu,SONG Fa-jun,YANG Guang-zhong(Laboratory for Natural Product Chemistry,College of Life Sciences,South Central University for Nationalities,Wuhan 430074,China)
Chemical constituents in the leave of Rhizophora stylosa L and their biological activities YANG Xu-hong~1,LI Huai-biao~1,CHEN Hong~1,LI Ping~2,YE Bo-ping~(1)(1.School of Life Science and Technology,China Pharmaceutical University,Nanjing 210009,China;2.Key Laboratory of Modern Chinese Medicines,Ministry of Education,China Pharmaceutical University,Nanjing 210038,China)
The roles of Kupffer cells in the development and regression of liver fibrosis WU Jun-yu,LIU Geng-tao(Institute of Materia Medica,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100050,China)
Progress on the studies of cyclic lipopeptides TANG Jin-shan~1,GAO Hao~2,DAI Yi~2,HONG Kui~3,YAO Xin-sheng~(1,2)(1.School of Traditional Chinese Materia Medica,Shenyang Pharmaceutical University,Shenyang 110016,China;2.Institutes of Traditional Chinese Medicine and Natural Products,Jinan University,Guangzhou 510632,China;3.State Key Laboratory of Tropic Crop Biotechnology,China Academy of Tropical Agricultural Science,Haikou 571101,China)
Significant role of poloxamer in drug transport across blood-brain barrier ZHANG Wei,FANG Xiao-ling(School of Pharmacy,Fudan University,Shanghai 200032,China)
Strategy of molecular drug design:hits,leads and drug candidates GUO Zong-ru(Institute of Materia Medica,Chinese Academy of Medical Sciences,Beijing 100050,China)
A limited sampling strategy of phenotyping probe midazolam to predict inhibited activities of hepatic CYP3A in rats ZHU Xue-hui~(1,2),JIAO Jian-jie~1,ZHANG Cai-li~1,LOU Jian-shi~(1),LIU Chang-xiao~3(1.Basic Medical College,2.College of Pharmaceutical Science,Tianjin Medical University,Tianjin 300070,China;3.Tianjin State Key Laboratory of Pharmacokinetics and Pharmacodynamics,Tianjin Institute of Pharmaceutical Research,Tianjin 300193,China)
Metabolism of nicousamide in rat and human liver in vitro SHENG Li,HU Jin-ping,CHEN Hui,LI Yan(Institute of Materia Medica,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100050,China)
Synthesis and antiinflammation activity of aromatic aminoketone compounds,a new type of PAF-receptor antagonist MOU Li-yuan~2,LIN Zi-yun~1,LIU Jie~1,ZHANG Qi-dong~1, ZHU Li-ya~(1),WANG Wen-jie~1,NIE Zhen-gui~1,HE Yu~1(1.Institute of Materia Medica,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100050,China;2.Center for Biophysical Science and Engineering,University of Alabama at Birmingham,1025 18~(th) Street South,Birmingham,AL 35294,USA)
Synthesis and antibacterial activity of imidazothiadiazoles and heterocyclic-amine Mannich-base hydrochloride HU Guo-qiang~(1),HOU Li-li~1,XIE Song-qiang~1,HUANG Wen-long~2,ZHANG Hui-bin~2(1.Institute of Pharmacy,Henan University,Kaifeng 475001,China;2.Center for New Drugs,China Pharmaceutical University,Nanjing 210009,China)
HPLC-MS/MS method for determination of sodium cromoglycate concentration in human plasma and its pharmacokinetics XU Xiao-yan~(1,2),ZHANG Rui~1,YUAN Gui-yan~1,WANG Ben-jie~1,LIU Xiao-yan~1,GUO Rui-chen~(1)(1.Institute of Clinical Pharmacology,Qilu Hospital of Shandong University,Jinan 250012,China;2.School of Pharmacy,Taishan Medical College,Tai'an 271016,China)
Determination of decapeptide LXT-101 in plasma by HPLC-MS/MS and its pharmacokinetics in Beagle dogs KONG Ai-ying,ZHANG Zhen-qing,QIAO Jian-zhong,ZHANG Fan,ZHOU Wen-xia,LIU Ke-liang,RUAN Jin-xiu(Key Lab of Drug Metabolism and Pharmacokinetics,Institute of Pharmacology and Toxicology,Academy of Military Medical Sciences,Beijing 100850,China)
Property of liposomal fusion induced by acid-sensitive polymer WANG Ru-tao~(1,2),CHEN Tao~(1,2),WANG Zhao~2,HUI Min-quan~(1,2),FU Jing-guo~(2,3)(1.Faculty of Life Sciences,Northwestern Polytechnical University,Xi'an 710072,China;2.Shaanxi Liposome Research Center,Xi'an 710075,China;3.Institute of Chemistry,Henan Academy of Sciences,Zhengzhou 450002,China)
Preparation of in situ gel systems for the oral delivery of ibuprofen and its pharmacokinetics study in Beagle dogs WU Rui-ling~(1,2),ZHAO Chun-shun~(1),XIE Jing-wen~1,YI Shao-ling~1,SONG Hong-tao~3,HE Zhong-gui~2(1.School of Pharmaceutical Sciences,Sun Yat-Sen University,Guangzhou 510080,China;2.School of Pharmacy,Shenyang Pharmaceutical University,Shenyang 110016,China;3.Fuzhou General Hospital of Nanjing Military Command,Fuzhou 350025,China)
Optimization of a novel mucoadhesive drug deliver system with ion-exchange resin core loaded with berberine hydrochloride using central composite design methodology CHEN Fei~1,ZHANG Yue~2,LIU Qiang~1,PANG Ming-zhi~1,YANG Xing-gang~1,PAN Wei-san~(1)(1.School of Pharmacy,Shenyang Pharmaceutical University,Shenyang 110016,China;2.College of Pharmacy,Second Military Medical University,Shanghai 200433,China)
Characterization of microstructure of ibuprofen-hydroxypropyl-β-cyclodextrin and ibuprofen-β-cyclodextrin by atomic force microscope WANG Li-juan,ZHU Zhao-jing,CHE Ke-ke,JU Feng-ge(School of Pharmacy,Chongqing University of Medical Sciences,Chongqing 400016,China)
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