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Comparative study on immunology of purging action of Radix Sophorae Flavescentis in two types spleen-dificiency model

Qu Changjiang,Lin Shuru,Xia Shujie,et al(133)  
The immunological changes of spleen-deficiency animal models under actions of Rhabart(Dai Huang) and Folium Cassial (Fan Xieye) was studied in the experiment.The results showed that there were obvious differences for the two groups of models in following items:Specific E rosette forming rate,immunoglobulin E (IgE) content,immunoglolbulin M (IgM) content,T lymphocytes subpopulation (Thy 1,2 ,lyt -2 ) ratio,interleukin(IL-2) activity,natural killer lymphocyte (Nkcell) activity,lymphocyte transformation rate.The results showed that pathomechanism of diarrhea due to spleen-deficiency was closely related immunological hypofunction.Meanwhile,it was also showed that there were differences for two drugs in pharmacodynamics and pharmacology.Folium Cassiael(Fan Xieye) was the preferred drugs for spleen-deficiency animal models.
【Fund】: 辽宁省教委科研基金
【CateGory Index】: R256.303
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