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《Acta Pharmaceutica Sinica》 2012-07
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Simultaneous quantitative analysis of four lignanoids in Schisandra chinensis by quantitative analysis of multicomponents by single marker

HE Feng-cheng1,2,LI Shou-xin1,2,ZHAO Zhi-quan1,2,DONG Jin-ping1,LIU Wu-zhan1,2,SU Rui-qiang1,2(1.Lunan Pharmaceutical Group Co.,Ltd.,2.State Key Laboratory of Generic Manufacture Technology of Chinese Traditional Medicine,Linyi 276006,China)  
The aim of the study is to establish a new method of quality evaluation and validate its feasibilities by the simultaneous quantitative assay of four lignanoids in Schisandra chinensis.A new quality evaluation method,quantitative analysis of multi-components by single marker(QAMS),was established and validated with Schisandra chinensis.Four main lignanoids,schisandrin,schisantherin A,deoxyschizandrin and γ-schizandrin,were selected as analytes and schisandrin as internal reference substance to evaluate the quality.Their contents in 13 different batches of samples,collected from different bathes,were determined by both external standard method and QAMS.The method was evaluated by comparison of the quantitative results between external standard method and QAMS.No significant differences were found in the quantitative results of four lignanoids in 13 batches of S.chinensis determined by external standard method and QAMS.QAMS is feasible for determination of four lignanoids simultaneously when some authentic standard substances were unavailable,and the developed method can be used for quality control of S.chinensis.
【Fund】: 国家重点基础研究发展计划(973计划)项目(2010CB735604)
【CateGory Index】: R284
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【References】
Chinese Journal Full-text Database 10 Hits
1 ZHANG Cheng-xian;YANG Hong-xia;CHEN Chu-jian;ZHANG Lu;LIN Li;LI Fen;Huzhou Institute for Food and Drug Control;;Simultaneous determination of four terpene lactones in Zhilining tablets by quantitative analysis of multi-components with a single marker[J];药物分析杂志;2015-12
2 ZHAO Wan-li;ZHANG Fang-fang;HUANG Xiao-qiang;LUO Fen-rong;CHEN Sai-nan;LI Xiao-yan;XU Wen;WU Shui-sheng;School of Pharmacy,Fujian University of Traditional Chinese Medicine;Centre of Biomedical Research&Development,Fujian University of Traditional Chinese Medicine;;Simultaneous Quantitative Analysis of Four Triterpenoids in Alismatis Rhizoma by Quantitative Analysis of Multi-components by Single Marker[J];中国药学杂志;2015-15
3 YANG Dongliang;MA Guizhi;WANG Juan;YUE Jiaqi;TENG Liang;YU Fusheng;Department of Pharmacy,the First Affiliated Hospital of Xinjiang Medical University;College of Pharmacy,Xinjiang Medical University;Xinjiang Huashengyuan Medical Technology Limited Company;;Quantitative analysis of multi-components with single marker for determination of components in Duma Granules[J];西北药学杂志;2015-03
4 WANG Jun-jun;ZHANG Li;GUO Qing;KOU Jun-ping;YU Bo-yang;GU Dan-hua;China Pharmaceutical University;Jiangsu Institute for Food and Drug Control;;Quantitative analysis of seven phenolic acids in eight Yinqiao Jiedu serial preparations by quantitative analysis of multi-components with single-marker[J];药学学报;2015-04
5 ZHOU Jian-liang;LIU Wei;TAN Chun-mei;ZHU Ming;MA Shuang-cheng;Zhejiang Institute for Food and Drug Control;National Institutes for Food and Drug Control;;Quality Control Study of Wuziyanzong Pills[J];中国药学杂志;2015-02
6 DOU Zhihua;AN Liping;SHI Kai;LUO Lin;ZHANG Lin;Third Affiliated Hospital of Nantong University;Nanjing University of Chinese Medicine;Nantong University;;Quality Evaluation of Schisandra chinensis Based on Combination of Fingerprint and QAMS[J];中国医药工业杂志;2014-12
7 LIU Shao-jing;LI Yan;ZHANG Ying;WANG Xiao-ning;YANG Li-bin;College of Pharmacy,Xi'an Medical University;;Quantitative analysis of three lignans in Schisandra sphenanthera Rehd. et Wils and Schizandra sinensis Baill. by RP-HPLC[J];应用化工;2014-11
8 Zhao Yiyi;Guo Hongzhu;Chen Yougen;Fu Xintong;Li Zheng;Tian Lu;Wang Jinghui;Beijing Institute for Drug Control;;A Comparative Study and Suggestion on Relative Correction Factor Produced by Different Methods in Quantitative Analysis of Multi-Components[J];中国药品标准;2014-04
9 ZHAO Qian;FENG Wei-hong;ZHANG Qi-wei;WANG Zhi-min;GAO Hui-min;LI Chun;YANG Li-xin;LIU Xiao-qian;YAN Li-hua;ZHU Jing-jing;CHEN Liang-mian;National Engineering Laboratory for Quality Control Technology of Chinese Herbal Medicines,Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences;;Feasibility study of QAMS for quantitative analysis of multiple structural types of ingredients in Zhizi Jinhua pill[J];中国中药杂志;2014-10
10 TANG An-fu;LI Si;WANG Yin-juan;XU Yun-yan;TANG Hao;WANG Shu-dong;Department of Pharmaceutical Preparation, Nanjing General Hospital of Nanjing Military Command of the PLA;;Progress and application of quantitative analysis of multi-components by single marker in pharmaceutical chemistry[J];中南药学;2014-02
China Proceedings of conference Full-text Database 2 Hits
1 WANG Ya;HUANG Ping;DI Liu-qing;ZHOU Ling-ling;CAI Bao-chang;LI Jun-song;College of Pharmacy,Nanjing University of Chinese Medicine;Jiangsu Provincial TCM Engineering Technology Research Center of High Efficient Drug Delivery System(DDS);Engineering Center of State Ministry of Education for Standardization of Chinese Medicine Processing;;A quantitative method using one marker for simultaneous assay of eleven alkloids in crude and wine-processed Coptidis Rhizoma[A];[C];2013
2 Xu Jing-jing;Liu Shi-qiao;Diao Yu-lin;Zhang En-hui;Han Dan;Ji Xin-yu;Zhong Kun-rui;Zhang Le;Liu Bin;School of Chinese Pharmacy,Beijing University of Chinese Medicine;;Application of the QAMs method in quality control and evaluation of traditional Chinese Medicine[A];[C];2013
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 PEI Gui-zhen;GUO Xin;ZHANG Xue-feng;GAN Yong-xiang;ZHANG Shu-lan;QI Xin-wen;Department of Pharmacy,Hospital of Xinjiang Production and Construction Corps;Medicine Department,Affiliated Traditional Medical Hospital,Xinjiang Medical University;;Simultaneous determination of costunolide,dehydrocostus lactone,emodin and chrysophanol in Liuweinengxiao capsules by HPLC[J];药物分析杂志;2015-02
2 LIU Wei;ZHOU Jian-liang;CHEN Bi-lian;ZHU Ming;Zhejiang Chinese Medical University;Zhejiang Institute for Food and Drug Control;;HPLC Fingerprint Analysis of Wuzi Yanzong Pills[J];医药导报;2014-10
3 Jianfang QIU;Jing LIN;Wen XU;Mingqing HUANG;Wanli ZHAO;Fenrong LUO;Xiaoyan LI;Shuisheng WU;School of Pharmacy,Fujian University of Traditional Chinese Medicine;Academy of Integrative Medicine,Fujian University of Traditional Chinese Medicine;;HPLC-DAD-ELSD Simultaneous Determination of Four Triterpenoids in RHIZOMA ALISMATIS[J];Medicinal Plant;2014-05
4 XU Jing-jing;XU Chao;LIU Bin;School of Chinese Pharmacy,Beijing University of Chinese Medicine;Jiangsu Nanxing Pharmaceutical Co. ,Ltd.;;Simultaneous Determination of Four Flavonoid Glycosides in Mentha haplocalyx Briq. by a Quantitative Analysis of Multi-Components by Single Marker[J];中国药学杂志;2014-03
5 LIU Wei;ZHOU Jian-liang;CHEN Bi-lian;ZHU Ming;Zhejiang Chinese Medical University;Zhejiang Institute for Food and Drug Control;;Simultaneous Determination of Five Ingredients in Wuzi Yanzong Pill by HPLC[J];中国实验方剂学杂志;2014-03
6 DOU Zhi-hua;An Li-ping;CHEN Min;MIAO Ying-xiang;QIAO Jin;CHEN Xia;FENG Yan;Third Affiliated Hospital of Nantong University;Nanjing University of Chinese Medicine;Nantong University;;Simultaneous Determination of Six Lignanoids in Schisandra chinensis by Quantitative Analysis of MultiComponents by Single Marker[J];中国药学杂志;2014-02
7 LU Lin-ling;QIAN Da -wei;GUO Jian -ming;YAN Hui;XU Bo -yi;SHA Mei;DUAN Jin -ao;Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization,Nanjing University of Chinese Medicine;·SZYY Group Pharmaceutical Limited;;A quantitative method using one marker for simultaneous assay of seven flavonoids in the flowers of Abelmoschus manihot[J];药物分析杂志;2013-12
8 LIU Xiang-nan;LI Ming-zhu;SHANG Xiao-na;SONG Ping-shun;ZHAO Jian-bang;School of Pharmacy,Lanzhou University;Gansu Institute for Food and Drug Control,Gansu Engineering Technology Research Center for Quality and Safety Evaluation of Traditional Chinese Medicine;;Determination of Six Active Ingredients in Gycyrrhizae Radix et Rhizoma by Quantitative Analysis of Multi-Components with a Single-Marker[J];中国实验方剂学杂志;2013-24
9 Zhou Jun;Pen Liu;Wu Xiaoming;Fu Yihe;Yichang Institute for Food and Drug Control;;Quality Standard for Zhilining Tablets[J];中国药师;2013-12
10 ZHOU Ti-qiang;FENG Su-xiang;LI Xiao-yu;BAI Yan;LI Jian-sheng;LI Juan;XU Peng;Henan University of Traditional Chinese Medicine;;Content Ditermination on Lignans in Schisandra Chinensis from Different Origin[J];医药导报;2013-12
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 Wei Liangbing;Shan Li;Gao Jiarong;Guo Mingfei;Jiang Nannan;Department of Pharmacy,the First Affiliated Hospital of Anhui University of Traditional Chinese Medicine(Three Grade Laboratory of Chinese Medicine Preparation of State Administration of Traditional Chinese Medicine);Anhui University of Traditional Chinese Medicine;;Research progress on the quality control of traditional Chinese medicine by the method of "quantitative analysis of multi-components by single marker" combined with fingerprint[J];中国基层医药;2018-09
2 BU Feng-jiao;JIANG Pin;ZHANG Hong-yan;XIANG Xiao-qiang;School of Pharmacy,Fudan University;China Pharmaceutical University;;Research progress in identification of multi-source Chinese materia medica: taking Schisandra sphenanthera and Schisandra chinensis as an example[J];时珍国医国药;2015-11
3 CHI Xu-ying;CUI Yue-xin;ZHANG Shu;DENG Hong;Institute of Materia Medica,Guangdong Pharmaceutical University/Guangdong Provincial Key Laboratory of Advanced Drug Delivery;;Quantitative analysis of 4 components in Isatidis Radix granules using single marker by QAMS[J];中国生化药物杂志;2015-10
4 MO Shu;ZHANG Hong-min;HAN Fu-man;WANG Li-xin;WANG Jin-yu;TONG Yan;FENG Wei-hong;LIU Jian-xun;Tianjin University of Traditional Chinese Medicine;Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences;Beijing Key Laboratory of Pharmacology of Chinese Materia Medica,Institute of Basic Medical Sciences of Xiyuan Hospital, China Academy of Chinese Medical Sciences;;Simultaneous Determination of Twelve Constituents in Quyu Huatan Tongmai Granules with Quantitative Analysis of Multi-components by Single-marker[J];中国实验方剂学杂志;2015-22
5 HU Yan;DOU Zhi-hua;Haimen People's Hospital;Nantong Third Affiliated Hospital of Nantong University;;Optimizing extraction of lignans from seed of Schisandra chinensis by multi-indexes[J];中南药学;2015-10
6 Zhang Fang;Gao Hongli;Hubei Institute for Nationalities School of Traditional Chinese Medicine;Special Care Hospital of Enshi Autonomous Prefecture;;Simultaneous Determination of Six Flavonoid Ingredients in Shuxuening Injection by Quantitative Analysis of Multi-components by Single-marker[J];中国药师;2015-10
7 HU Tieshan;Department of Pharmacy, Jiangxi Province hospital of Traditional Chinese medicine;;Quantitative Analysis of the Baicalin and Wogonoside Ingredients in Gardenia Golden Flower Pill[J];中国中医药现代远程教育;2015-17
8 MA Bai-ping;KANG Li-ping;PANG Xu;YAN Ren-yi;Institute of Radiation Medicine,Academy of Military Medical Sciences;State Key Laboratory of Dao-di Herbs,National Resource Center for Chinese Materia Medica,China Academy of Chinese Medical Sciences;Ovation Health Science and Technology Co.Ltd.,ENN Group;;Techniques and strategies for characterization and isolation of chemical components of traditional Chinese medicines[J];国际药学研究杂志;2015-04
9 HUANG Qun-lian;LUO Ying;LI Qin;SUN Qin;Affiliated Hospital of Sichuan Medical University;School of Pharmacy,Sichuan Medical University;;Study on applicability of QAMS to Phellodendri Chinensis Cortex formula granules and cork pieces[J];中国医院药学杂志;2015-16
10 WU Chun-yan;GENG Shu;YI Xiao-jiao;CHEN Jia-shan;JIANG Ke-qiu;WU Yong-jiang;College of Pharmaceutical Sciences,Zhejiang University;;Recent Advances in Quality Analysis and Evaluation of Traditional Chinese Medicines[J];理化检验(化学分册);2015-07
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