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Clinical observation of mecobalamin acupoint injection with acupuncture for treating intractable facial paralysis

WU Jun,YANG Li-xia,ZHOU Xian-gang(Department of Neurology,People′s Hospital of Longchang County,Longchang,Sichuan 642150,China)  
Objective To assess the efficacy and safety of mecobalamin acupoint injection with acupuncture for treating intractable facial paralysis.Methods Seventy patients with intractable facial paralysis were randomly divided into treatment group and control group,35 patients in each group.The treatment group was treated with mecobalamin acupoint injection with acupuncture treatment,and the control group with single acupuncture treatment.40d later,their therapeutic effects were observed.Results All the results were analyzed on the basis of intention-to-treat(ITT) and per-protocol population(PP),the total effective rate was 77.14% or 81.26% in the treatment group and 51.43% or 56.67% in the control group.There was a statistical difference between the two groups(P0.05).ITT and PP analysis revealed similar results.No adverse effect was found in the observation.Conclusion The efficacy and safety of mecobalamin acupoint injection with acupuncture for treatment of intractable facial paralysis are difinite.It is worthy of spreading in clinic.
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