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Study preliminary on the anti-tumor effect of the extract of Tetrastigma hemsleyanum Diels et.Gilg

DING Li,JI Qi-xiong(Zhejiang Pharmaceutical College,Ningbo 315100,China)  
OBJECTIVE To estimate the anti-tumor activity of the extract of Tetrastigmatis hemsleyani Diels et Gilg.METHODS It was measured by methyl thiazolyltet razolium(MTT) colorimetric assay to screen the anti-tumor effect of the extracts of Tetrastigmatis hemsleyani Diels et Gilg on different tumor cell lines in vitro.RESULTS The alcohol extract and four fraction from Tetrastigmatis hemsleyani Diels et Gilg had variable inhibitory effect on different tumor cell lines.Chloroform part and petroleum ether part had more remarkable anti-tumor activity in vitro than ethyl acetate part and 1-Butanol part.CONCLUSION Chloroform part and petroleum ether part,which are considered as active parts of Tetrastigmatis hemsleyani Diels et Gilg,had a significant influence on cell activity in a dose-dependent manner.
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