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Studies on nucleoside constituents of Jellyfish Stomopholus meleagris

CAI Yang-peng,LIU Lu-lu,YAN Yu-xia,LI Ping-lin,LI Ba-fang(College of Food Science and Engineering,Ocean University of China,Qingdao 266003,China)  
Objective For further utilization and exploitation of jellyfish resource,nucleoside constituents from jellyfish Stomopholus meleagris were investigated.Methods Methanol extracts of fresh jellyfish was partitioned successively with petroleum ether,ethyl acetate,and n-butanol.Then silica gel chromatography,Sephadex LH-20 gel filtration and PTLC were performed for the isolation and purification of the compounds,and GC-MS,ESIMS,NMR analyses as well as data comparison with reported literatures were applied for the structure elucidation.Results Six compounds were isolated and determined from jellyfish: thymine(1),2'-O-methyluridine(2),uracil(3),2'-deoxythymidine(4),2'-deoxyuridine(5),uridine(6).Conclusion All the compounds obtained were purified and identified from jellyfish Stomopholus meleagris for the first time.
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