Full-Text Search:
Home|About CNKI|User Service|中文
Add to Favorite Get Latest Update

The Relationship Between Cell Cycle Control Gene cyclin D1 and p16 and Lung Cancer

QIU Hong,SU Chang-qing. Department of Biochemistry,Nanjing 81 hospital,Nanjing,210002  
Objective To study the relationship between cyclin D1,p16 gene and lung cancer.Methods cyclin D1 and p16 genes in 40 cases of lung cancer were studied by multiplex PCR.Results The positive rate of cyclin D1 gene and p16 gene in lung cancer was 55.0%(22/40) and 65.0%(26/40) respectively.The positive rates of the two genes were related to lymph node metastasis and clinical stage of lung cancer.Conclusion cyclin D1 and p16 genes play an important role in lung cancer.Amplification of cyclin D1 gene and deletion of p16 gene are related to the high activity of cancer cells.
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
©CNKI All Rights Reserved