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Determination and analysis on multimark of test of the patients with endemic fluorosis

WAN Gui min, MO Zhi ya, LIU Zhong jie, et al (Institute of Endemic Fluorosis Research, Harbin Medical University, Harbin 150086, China)  
Objective To study the significant test of diagnosing endemic fluorosis.Methods Twenty one of routine and biochemical marks of blood and urine of 600 cases of the patients with different degree endemic fluorosis were determined and analysed.Results The prevalence rate of anemia has rising with becoming heavier the disease degree of endemic fluorosis.The averge level of fluoride in serum and urine were significantly higher than the reference value.The calcium in serum decrease,and the phosphorus increase.The excreted amount of urinary calcium increase in the severe patients.AKP rise along with becoming heavider of the disease degree.The content of total protein and albumin in serum was within normal range,but globulin evidently raises.The average of T 3 and T 4 was lower than the reference value,especially that of the middle,severe patients were obviously lower. Conclusions The RBC,Hb,serum calcium,phosphorus,AKP,urinary calcium,globulin,T 3 and T 4 were signifiantly marks of diagnosing endemic fluerosis.
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