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The Evaluation of MRS Exhibition Feature of MS

SUN Jia-yu,XIAO Jia-he,ZHOU Xiang-ping,et al. (Department of Radiology,West China Hospital,Sichuan University,Chengdu Sichuan 610041,China)  
Objective:To investigate the image features and its diagnostic value of MS by MRS.Methods:SE,TSE,FLAIR and 1H-MRS images were obtained from 24 patients with MS (13 male,11 female,age range 10-59year,average age 34.5years).The raw spectroscopy data were evaluated using the Siemens Syngo MR 2002B software package.Integral area under each metabolite peak and its ratio with that of Cr were calculated.Metabolites involved in the analysis included NAA,Cr,Cho,MI,and then the results of the lesion,the area around the lesion and the normal brain tissue were analysed.Resullts:NAA in the lesion,the area around the lesion and of normal brain tissue were different significantly(P0.05).There was no significant difference among Cho,Cr,Mi,Cho/Cr and Mi/Cr(0.05).NAA/Cr was demonstrated significant difference between the normal brain tissue and the lesion,or the area around the lesion(P0.05).Conclusion:NAA was significantly different among the lesion,the area around the lesion and the normal brain tissue.MRS was very important for diagnosis of MS.
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