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The effectiveness of noninvasive positive pressure ventilation in chronic obstructive pulmonary disease with respiratory failure

Deng Jie,Tang Yu-ling(Department of Respiratory,the First Hospital of Changsha,Hunan Changsha 410008,China)  
Aim: To investigate the effectiveness of noninvasive positive pressure ventilation(NPPV)in chronic obstructive pulmonary disease(COPD) with severe respiratory failure.Methods: Twenty-eight patients who due to AECOPD complicated with severe type II respiratory failure and received NPPV therapy were enrolled as NPPV group.Other similar 22 cases who had not recieved NPPV therapy served as control group.Arterial blood gases before and after treatment,the duration of the arterial blood gases improved,the duration of hospitalization and inbution rate were abserved.Results: The arterial pH,paO2,and paCO2 imprvoed significantly after treatment compared with the controlled group(P0.05).Compared with the controlled group,the attaining time of the arterial blood gases improved was significantly shorter(7±4 vs 15±7 days,P0.05),the duration of hospitalization was significantly shorter(14±5 vs 27±6 days,P0.05)and the inbution rate was significantly lower(3.5% vs 22.8%,P0.05)in the NPPV group.Conclusion:It is clinical sure that used BiPAP ventilator-assisted to treat COPD with respiratory failure.The rate of trachea intubation is decreased.It is conducive to patients rehabilitation.
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