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Comparing study of cervical cancer screening system and liquid-based cytology test in the screening of cervical lesions

Lü Siji,Huang Lixia,Zhao Xin,et al.Department of Obstetrics and Gynecology,East Hospital,Tongji University,Shanghai 200120  
Objective:To study the clinical value of cancer screening system(TruScreen)and liquid-based cytology test(LCT)in the diagnosis of cervical lesions.Methods:487 cases of patients were screened by TruScreen and LCT based on the pathology result as a golden standard.To compare the sensitivity,specificity and fake negative rate of the two methods.Results:The postitive result cases of TruScreen and LCT were 229 and 42,the postitive result cases of pathlology were 30.The sensitivity of TruScreen,LCT and TruScreen combined with LCT were 54.7%,93.9% and 50.5%,the specificity were 54.7%,93.9% and 50.5%,the fake negative rates were 26.7%,53.3% and 10% respectively.The difference of sensitivity between TruScreen,TruScreen combined with LCT was significant(P0.05).And the difference of sensitivity between TruScreen and TruScreen combined with LCT was not significant(P0.05).Conclusions:The value of TruScreen in dignosisis of cervical lesions is better than LCT in this research.As a new cervical lesion screening technology,TruScreen may be more effective in China.
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